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Meg Ryan has published a heartfelt tribute to the deceased director Rob Reiner, under whose direction she worked in the hit romantic comedy When Harry Met Sally.

A Heartbreaking Event

Reiner was located lifeless with his wife, Michele Singer Reiner, at their home in Los Angeles at the weekend.

“We will miss this man so deeply…” Ryan wrote on Instagram, accompanying a photo of them together. “Our gratitude, Rob and Michele, for your faith in true love, stories, and joy. We appreciate your faith in human goodness and your deep patriotism.”

Court Case Developments

Reiner’s son Nick, 32, is accused of two counts of first-degree murder and made a court appearance today. He’s being incarcerated with no bail set. It’s been reported that Reiner’s daughter Romy discovered her father deceased.

“I have to believe that their story will not end with this impossible tragedy, that some good may come, some awareness raised,” Ryan went on to write. “I don’t know, but my guess is that they would want that to be hopeful and humane, to be something that brings us all to a greater understanding of one another and to some peace.”

Children Share Their Grief

Reiner’s other children Jake and Romy issued words today. “Words cannot even begin to describe the unimaginable pain we are experiencing every moment of the day,” they said. “The tragic, shattering loss of our parents is an experience no one should have to face. They were more than parents; they were our closest confidants.”

Peers Pay Their Respects

Ryan’s co-star, Billy Crystal, also paid tribute to Reiner through a message shared yesterday together with remarks by Larry David, Martin Short and Albert Brooks.

“No one matched his comic instinct, his dedication to rhythmic dialogue, or his elegant sharpening of drama,” the tribute noted. “He adored his actors. He elevated his writers. His greatest gift was freedom. If you had an idea, he listened, he brought you into the process. They always felt they were working as a team. To be in his hands as a film-maker was a privilege but that is only part of his legacy.”

A Storied Career

When Harry Met Sally was a box office and critical triumph in 1989, earning over $93 million globally and securing Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner was introduced to Michele Singer Reiner during the production of When Harry Met Sally. The pair were connected through Barry Sonnenfeld, a fellow filmmaker and pal.

Reiner’s notable filmography also included classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were married for 36 years.